Toulouse cruised into the quarters with five tries.
Scrum-half Jean-Baptiste Elissalde edged them ahead with a penalty.
Vincent Clerc grabbed the first touchdown in the 10th minute. Then Elissalde converted.
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Phil Godman eased the jitters with a penalty and in the 35th minute Clerc got a second try from a grubber kick by Elissalde.
Florian Fritz burst through for the next score, Elissalde converting. Yves Donguy and Salvatore Perugini pounced for further Toulouse tries.
Ben Gissing ploughed over for a Gunners' consolation effort.
